Dorly de Freitas Buchi

Homeopathy Science

About Us

Dorly de Freitas Buchi, a renowned Brazilian researcher, holds a Ph.D. in Biological Sciences (Biophysics) from the Federal University of Rio de Janeiro. Her solid academic background is reflected in the publication of several scientific articles in the field of Cell Biology. Professor, for more than 40 years at the Federal University of Paraná, she combines extensive experience in higher education, both in undergraduate and graduate courses, and effective contributions in the sphere of the university administration. Her orientation activities are remarkable, from scientific initiation to doctorate, having promoted the training of a large number of young scientists.

Despite this exemplary academic trajectory, what makes Dorly a special human being are her unique qualities: loyalty, courage, tenderness, and tenacity. Woman, mother, sister, and friend, she is endowed with profound sensitivity, a conciliatory spirit, and the ability to aggregate people and ideals around a greater good. Her respect for life, in all its forms, has always guided her in search of health promotion and a better life for all. And so, in her continuous overcoming of challenges, guided by an acute scientific curiosity and her non-conformity with the paradigms and limitations of traditional medicine, in an untiring spirit and an unwavering purpose of serving collective interests, firmly carried out research based on highly diluted drugs and complex biological response modifiers. A significant part of the results of her efforts and her holistic view is presented in this book which, as an author, proposes to contribute to life, health, and the construction of happiness for all.

About Homeopathy

Immune System and Homeopathy Studies using macrophages treated with different homeopathic medicines have resulted in a significant increase in the activated/resident macrophage ratio compared to control groups (water, hydroalcoholic solution, and untreated). Different macrophage receptors were altered, both in expression and distribution, in addition to altering the production and release of different cytokines and reactive oxygen and nitrogen species…

Last posts we sent to the blog

Homeopathy Science

  • Like cures like: This principle states that a substance that can cause symptoms in a healthy person can cure those same symptoms in a sick person. For example, if a person gets a rash from contact with poison ivy, then a homeopathic remedy made from poison ivy might be used to treat a rash with similar symptoms.

  • The law of minimums: This principle states that the smaller the dose of a remedy, the greater its effect. Homeopathic remedies are often diluted to very high levels, but practitioners believe that this dilution makes them more effective.

  • The single remedy: This principle states that only one remedy should be given at a time, so that its effects can be clearly observed.

  • The totality of symptoms: This principle states that the remedy should be chosen based on the whole picture of the patient’s symptoms, not just the physical symptoms. This includes the patient’s emotional and mental state, as well as their lifestyle and preferences.

My Book on Amazon

To know more about homeoptahy

Visit our blog

The existence and unexpected pathways in my life.

In this book, I tell the story of my life and my relationship with science, and especially how this journey resulted in 20 years of basic research in homeopathy.

Address

Gallusstrasse 1a 8730 Uznach

Email

buchi@imagem.ch

Abstract I
A homeopathic complex medication (HCM), with immunomodulatory properties, is recommended for patients with depressed immune systems. Previous studies demonstrated that the medication induces an increase in leukocyte number. The bone marrow microenvironment is composed of growth factors, stromal cells, an extracellular matrix and progenitor cells that differentiate into mature blood cells. Mice were our biological model used in this research. We now report in vivo immunophenotyping of total bone marrow cells and ex vivo effects of the medication on mononuclear cell differentiation at different times. Cells were examined by light microscopy and cytokine levels were measured in vitro. After in vivo treatment with HCM, a pool of cells from the new marrow microenvironment was analyzed by flow cytometry to detect any trend in cell alteration. The results showed decreases, mainly, in CD11b and TER-119 markers compared with controls. Mononuclear cells were used to analyze the effects of ex vivo HCM treatment and the number of cells showing ring nuclei, niche cells and activated macrophages increased in culture, even in the absence of macrophage colony-stimulating factor. Cytokines favoring stromal cell survival and differentiation in culture were induced in vitro. Thus, we observe that HCM is immunomodulatory, either alone or in association with other products.    https://www.hindawi.com/journals/ecam/2011/212459/



Abstract II
In the search for new therapies novel drugs and medications are being discovered, developed and tested in laboratories. Highly diluted substances are intended to enhance immune system responses resulting in reduced frequency of various diseases, and often present no risk of serious side-effects due to its low toxicity. Over the past years, our research group has been investigating the action of highly diluted substances and tinctures on cells from the immune system. We have developed and tested several highly diluted tinctures and here we describe the biological activity of M1, M2, and M8 both in vitro in immune cells from mice and human, and in vivo in mice. Cytotoxicity, cytokines released and NF-κB activation were determined after in vitro treatment. Cell viability, oxidative response, lipid peroxidation, bone marrow, and lymph node cells immunophenotyping were accessed after mice in vivo treatment.
None of the highly diluted tinctures tested were cytotoxic to macrophages or K562. Lipopolysaccharide (LPS)-stimulated macrophages treated with all highly diluted tinctures decreased tumor necrosis factor alpha (TNF-α) release and M1, and M8 decreased IFN-γ production. M1 has decreased NF-κB activity on TNF-α stimulated reporter cell line. In vivo treatment lead to a decrease in reactive oxygen species (ROS), nitric oxide (NO) production was increased by M1, and M8 and lipid peroxidation were induced by M1 and M2. All compounds enhanced the innate immunity, but M1 also augmented acquired immunity and M2 diminished B lymphocytes, responsible for acquired immunity. Based on the results presented here, these highly diluted tinctures were shown to modulate immune responses. Even though further investigation is needed there is an indication that these highly diluted tinctures could be used as therapeutic interventions in disorders where the immune system is compromised.   https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/1472-6882-11-101

Abstract III
Melanoma is the most aggressive form of skin cancer and the most rapidly expanding cancer in terms of worldwide incidence. Chemotherapeutic approaches to treat melanoma have had only marginal success. Previous studies in mice demonstrated that a high diluted complex derived from Calcarea carbonica (M8) stimulated the tumoricidal response of activated lymphocytes against B16F10 melanoma cells in vitro. Here we describe the in vitro inhibition of invasion and the in vivo anti-metastatic potential after M8 treatment by inhalation in the B16F10 lung metastasis model. We found that M8 has at least two functions, acting as both an inhibitor of cancer cell adhesion and invasion and as a perlecan expression antagonist, which are strongly correlated with several metastatic, angiogenic and invasive factors in melanoma tumors. The findings suggest that this medication is a promising non-toxic therapy candidate by improving the immune response against tumor cells or even induce direct dormancy in malignancies.  https://www.ncbi.nlm.nih.gov/pubmed/20338038

https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-10-113