Dorly de Freitas Buchi

Homeopathy Science

About Us

Dorly de Freitas Buchi, a renowned Brazilian researcher, holds a Ph.D. in Biological Sciences (Biophysics) from the Federal University of Rio de Janeiro. Her solid academic background is reflected in the publication of several scientific articles in the field of Cell Biology. Professor, for more than 40 years at the Federal University of Paraná, she combines extensive experience in higher education, both in undergraduate and graduate courses, and effective contributions in the sphere of the university administration. Her orientation activities are remarkable, from scientific initiation to doctorate, having promoted the training of a large number of young scientists.

Despite this exemplary academic trajectory, what makes Dorly a special human being are her unique qualities: loyalty, courage, tenderness, and tenacity. Woman, mother, sister, and friend, she is endowed with profound sensitivity, a conciliatory spirit, and the ability to aggregate people and ideals around a greater good. Her respect for life, in all its forms, has always guided her in search of health promotion and a better life for all. And so, in her continuous overcoming of challenges, guided by an acute scientific curiosity and her non-conformity with the paradigms and limitations of traditional medicine, in an untiring spirit and an unwavering purpose of serving collective interests, firmly carried out research based on highly diluted drugs and complex biological response modifiers. A significant part of the results of her efforts and her holistic view is presented in this book which, as an author, proposes to contribute to life, health, and the construction of happiness for all.

About Homeopathy

Immune System and Homeopathy Studies using macrophages treated with different homeopathic medicines have resulted in a significant increase in the activated/resident macrophage ratio compared to control groups (water, hydroalcoholic solution, and untreated). Different macrophage receptors were altered, both in expression and distribution, in addition to altering the production and release of different cytokines and reactive oxygen and nitrogen species…

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Homeopathy Science

  • Like cures like: This principle states that a substance that can cause symptoms in a healthy person can cure those same symptoms in a sick person. For example, if a person gets a rash from contact with poison ivy, then a homeopathic remedy made from poison ivy might be used to treat a rash with similar symptoms.

  • The law of minimums: This principle states that the smaller the dose of a remedy, the greater its effect. Homeopathic remedies are often diluted to very high levels, but practitioners believe that this dilution makes them more effective.

  • The single remedy: This principle states that only one remedy should be given at a time, so that its effects can be clearly observed.

  • The totality of symptoms: This principle states that the remedy should be chosen based on the whole picture of the patient’s symptoms, not just the physical symptoms. This includes the patient’s emotional and mental state, as well as their lifestyle and preferences.

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The existence and unexpected pathways in my life.

In this book, I tell the story of my life and my relationship with science, and especially how this journey resulted in 20 years of basic research in homeopathy.


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Epigenetics is the study of how your behaviors and environment can cause changes that affect the way your genes work. It is the study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself.

Several lifestyle factors have been identified that might modify epigenetic patterns, such as diet, obesity, physical activity, tobacco smoking, alcohol consumption, environmental pollutants, psychological stress, and working on night shifts.

The Integrative Medicine (IM) model not only considers the holistic perspective of the physiological components of the individual, but also includes psychological and mind-body aspects. They propose that IM’s ability to affect healing is due at least in part to epigenetic mechanisms.

This hypothesis is based on a mounting body of evidence that demonstrates a correlation between the physical and mental effects of Integrative Medicine and modulation of gene expression and epigenetic state.

Since ancient times human civilizations have made use of various natural resources to restore health, so IM practices have been commonly used to improve health and ameliorate pathological conditions. It is only in recent years that the humanity has focused on unraveling the underlying mechanism in the light of molecular genetics and biochemistry.

Epigenetic mechanisms include chromatin folding and attachment to the nuclear matrix, packaging of DNA, covalent modifications of histone tails (acetylation, methylation, and phosphorylation), and DNA methylation, which taken together provide a plausible explanation for nongenetic disease transmission.

The idea that IM possesses the power to regulate the epigenome to achieve its therapeutic effects is novel and needs further development and could play a crucial role in developing future research strategies in health care.

You can read more about in a review article “Epigenetic Mechanisms of Integrative Medicine”,