Despite this exemplary academic trajectory, what makes Dorly a special human being are her unique qualities: loyalty, courage, tenderness, and tenacity. Woman, mother, sister and friend, she is endowed with profound sensitivity, a conciliatory spirit and the ability to aggregate people and ideals around a greater good. Her respect for life, in all its forms, has always guided her in search of health promotion and a better life for all. And so, in its continuous overcoming of challenges, guided by an acute scientific curiosity and its non-conformity with the paradigms and limitations of traditional medicine, in an untiring spirit and an unwavering purpose of serving collective interests, firmly carried out research based on highly diluted drugs and complex biological response modifiers. A significant part of the results of his efforts and his holistic view is presented in this book which, as an author, proposes to contribute to life, health and the construction of happiness for all.
Dra. Dorly de Freitas Buchi, the renowned Brazilian researcher, holds a Ph.D. in Biological Sciences (Biophysics) from the Federal University of Rio de Janeiro. His solid academic background is reflected in the publication of several scientific articles in the field of Cell Biology. Professor, for more than 40 years at the Federal University of Paraná, she combines extensive experience in higher education, both in undergraduate and graduate courses, and effective contributions in the sphere of the university administration. Its orientation activities are remarkable, from scientific initiation to doctorate, having promoted the training of a large number of young scientists.
Calcarea carbonica derivative complex (M8) as adjuvant treatment of inflammatory mammary carcinoma in a dog
Inflammatory mammary carcinoma (IMC) is locally aggressive, fast growing, a highly malignant tumor that affects humans and dogs. Affected dogs usually are presented with generalized edema, pain, erythema, and skin ulceration in mammary glands.
Surgery is not recommended, and effective treatment has not been established. Calcarea carbonica derivative complex (M8) is a complex high diluted homeopathic medicine. M8 demonstrated anticancer properties in a murine model, by improving innate immune response against tumor cells. At Veterinary Hospital of Federal University of Paraná, Brazil, it was used M8 in association with pyroxican (non-steroidal anti-inflammatory drug) to treat a dog with inflammatory mammary carcinoma.
A 7 years old, mixed breed intact female dog was presented with inflammation of mammary glands which was treated for mastitis (cephalexin and metergoline) without clinical improvement. Clinical examination revealed erythema, increased skin warmth, pain on palpation, and plaque involving the 4th and 5th left mammary glands. Abdominal ultrasound and serum biochemistry were unremarkable.
Cytological interpretation was a malignant epithelial neoplasm. Diagnosis of IMC was based on clinical signs and cytopathology. The dog was treated with oral (0.5 mL) and topical hydrogel M8 twice a day for 15 days, and pyroxican, 0.3mg/kg/24h. Clinical improvement was observed 7 days after starting treatment. Until present date dog has no clinical signs of IMC and does not show signs of disease progression.
Results: Clinical improvement was observed 7 days after starting treatment. Until present date dog has no clinical signs of IMC and does not show signs of disease progression.
Conclusion: The present report suggests that M8 associated with pyroxican contributes to improvement of IMC dog’s quality of life and survival rate.
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