My Life With Science!

Despite this exemplary academic trajectory, what makes Dorly a special human being are her unique qualities: loyalty, courage, tenderness, and tenacity. Woman, mother, sister and friend, she is endowed with profound sensitivity, a conciliatory spirit and the ability to aggregate people and ideals around a greater good. Her respect for life, in all its forms, has always guided her in search of health promotion and a better life for all. And so, in its continuous overcoming of challenges, guided by an acute scientific curiosity and its non-conformity with the paradigms and limitations of traditional medicine, in an untiring spirit and an unwavering purpose of serving collective interests, firmly carried out research based on highly diluted drugs and complex biological response modifiers. A significant part of the results of his efforts and his holistic view is presented in this book which, as an author, proposes to contribute to life, health and the construction of happiness for all.

The presence of the unexpected in my life!

Dra. Dorly de Freitas Buchi, the renowned Brazilian researcher, holds a Ph.D. in Biological Sciences (Biophysics) from the Federal University of Rio de Janeiro. His solid academic background is reflected in the publication of several scientific articles in the field of Cell Biology. Professor, for more than 40 years at the Federal University of Paraná, she combines extensive experience in higher education, both in undergraduate and graduate courses, and effective contributions in the sphere of the university administration. Its orientation activities are remarkable, from scientific initiation to doctorate, having promoted the training of a large number of young scientists.

SCIENCE is exploring the potential of INNATE IMMUNITY to benefit animal health. The rational basis of immunomodulation directed to the innate immune system is related to its ability to respond to a wide variety of pathogens, in contrast to specific therapies such as vaccines and antibiotics.

The innate immune response is responsible for trying to block the replication of pathogens before the onset of the disease. It is a rapid and nonspecific response involving a complex network of biochemical and cellular pathways, which actively recognize and remove invading pathogens, as well as activates the ADAPTIVE IMMUNE RESPONSE resulting in lasting protection. The innate immune response is also involved in tissue repair processes, such as healing and bone remodeling, as well as participating in the immunological control of emerging tumors and processes of inhibition of tumor progression. Thus, the modulation of innate immunity has the potential for preventive, therapeutic or adjuvant use.

Highly diluted natural drugs were studied in research centers in Brazilian universities. Several modulatory effects of the innate immune response have been observed in vitro and in vivo studies using animal models. These immunomodulatory actions have also been demonstrated in the human and veterinary medical clinic.


Inflammatory Breast Carcinoma Canine treated with oral medication (drops) and topical (gel). (A) Clinical signs of breast carcinoma prior to treatment. (B) After 7 days of treatment. (C) No clinical signs after 60 days of treatment.

Clinical case: Highly diluted natural drug (M 8) in the treatment of Mammary Inflammatory Carcinoma in dogs – Veterinary Hospital – UFPR

SILVA D.M. et al. Oral, topical, and inhalation of Calcarea carbonica derivative complex (M8) to treat

inflammatory mammary carcinoma in dogs. Int J High Dilution Res 2012, 11(40). Proceedings of the XXVI GIRI Symposium; 2012 Florence (Italy)