Dorly de Freitas Buchi, a renowned Brazilian researcher, holds a Ph.D. in Biological Sciences (Biophysics) from the Federal University of Rio de Janeiro. Her solid academic background is reflected in the publication of several scientific articles in the field of Cell Biology. Professor, for more than 40 years at the Federal University of Paraná, she combines extensive experience in higher education, both in undergraduate and graduate courses, and effective contributions in the sphere of the university administration. Her orientation activities are remarkable, from scientific initiation to doctorate, having promoted the training of a large number of young scientists.
Despite this exemplary academic trajectory, what makes Dorly a special human being are her unique qualities: loyalty, courage, tenderness, and tenacity. Woman, mother, sister, and friend, she is endowed with profound sensitivity, a conciliatory spirit, and the ability to aggregate people and ideals around a greater good. Her respect for life, in all its forms, has always guided her in search of health promotion and a better life for all. And so, in her continuous overcoming of challenges, guided by an acute scientific curiosity and her non-conformity with the paradigms and limitations of traditional medicine, in an untiring spirit and an unwavering purpose of serving collective interests, firmly carried out research based on highly diluted drugs and complex biological response modifiers. A significant part of the results of her efforts and her holistic view is presented in this book which, as an author, proposes to contribute to life, health, and the construction of happiness for all.
Immune System and Homeopathy Studies using macrophages treated with different homeopathic medicines have resulted in a significant increase in the activated/resident macrophage ratio compared to control groups (water, hydroalcoholic solution, and untreated). Different macrophage receptors were altered, both in expression and distribution, in addition to altering the production and release of different cytokines and reactive oxygen and nitrogen species…
Like cures like: This principle states that a substance that can cause symptoms in a healthy person can cure those same symptoms in a sick person. For example, if a person gets a rash from contact with poison ivy, then a homeopathic remedy made from poison ivy might be used to treat a rash with similar symptoms.
The law of minimums: This principle states that the smaller the dose of a remedy, the greater its effect. Homeopathic remedies are often diluted to very high levels, but practitioners believe that this dilution makes them more effective.
The single remedy: This principle states that only one remedy should be given at a time, so that its effects can be clearly observed.
The totality of symptoms: This principle states that the remedy should be chosen based on the whole picture of the patient’s symptoms, not just the physical symptoms. This includes the patient’s emotional and mental state, as well as their lifestyle and preferences.
In this book, I tell the story of my life and my relationship with science, and especially how this journey resulted in 20 years of basic research in homeopathy.
Inflammatory mammary carcinoma (IMC) is locally aggressive, fast growing, a highly malignant tumor that affects humans and dogs. Affected dogs usually are presented with generalized edema, pain, erythema, and skin ulceration in mammary glands.
Surgery is not recommended, and effective treatment has not been established. Calcarea carbonica derivative complex (M8) is a complex high diluted homeopathic medicine. M8 demonstrated anticancer properties in a murine model, by improving innate immune response against tumor cells. At Veterinary Hospital of Federal University of Paraná, Brazil, it was used M8 in association with pyroxican (non-steroidal anti-inflammatory drug) to treat a dog with inflammatory mammary carcinoma.
A 7 years old, mixed breed intact female dog was presented with inflammation of mammary glands which was treated for mastitis (cephalexin and metergoline) without clinical improvement. Clinical examination revealed erythema, increased skin warmth, pain on palpation, and plaque involving the 4th and 5th left mammary glands. Abdominal ultrasound and serum biochemistry were unremarkable.
Cytological interpretation was a malignant epithelial neoplasm. Diagnosis of IMC was based on clinical signs and cytopathology. The dog was treated with oral (0.5 mL) and topical hydrogel M8 twice a day for 15 days, and pyroxican, 0.3mg/kg/24h. Clinical improvement was observed 7 days after starting treatment. Until present date dog has no clinical signs of IMC and does not show signs of disease progression.
Results: Clinical improvement was observed 7 days after starting treatment. Until present date dog has no clinical signs of IMC and does not show signs of disease progression.
Conclusion: The present report suggests that M8 associated with pyroxican contributes to improvement of IMC dog’s quality of life and survival rate.
Figure 1. Female dog with clinical and cytopathology signs of IMC. It presented a mammary inflammation of 4th and 5th left mammary glands. Figure 2. Sixty days after initial treatment there were no clinical signs of IMC
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